Water is the primary component of biological samples relevant to life sciences. With the Opolette 2940, a micro-sized cross-section can be desorbed while keeping sample constituents intact. Ionization can occur directly or through the addition of a secondary ionization source, followed by mass spectrometric analysis. The OpoletteTM 2940 is designed for custom or commercial ion source integration. An SDK is available to integrate laser functions into instrument software. The laser can be factory tuned to other absorption peaks between 2600 and 3450 nm.